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Supported by an independent educational grant from Jazz Pharmaceuticals, Inc.

Anticholinergics and VMAT-2 Inhibitors: Different MOAs, Different Results

DECEMBER 13, 2024

This animated video visually explores the distinct mechanisms of action (MOAs) of anticholinergics and VMAT-2 inhibitors in managing tardive dyskinesia. It highlights the efficacy and safety differences between the two drug classes, emphasizing how VMAT-2 inhibitors target dopamine dysregulation at the synaptic level, resulting in more targeted and effective symptom relief compared to the broader and less specific effects of anticholinergics.